Author

R. Lories

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:imaging· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. De Roover· 2 shared A. Sermon· 2 shared F. Cornelis· 2 shared S. Monteagudo· 2 shared A. Escribano· 1 shared A. Esrafilian· 1 shared A. Hillen· 1 shared C. Cherifi· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

A. De Roover

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Author profile →

4 papers

Recent·Most cited

Joint and tissue mechanics in post-traumatic osteoarthritis: insights from the rat model

J. Piet, S. A. Elahi, A. Esrafilian, F. Mielke, M. Van Nuffel, G. A. Orozco, S. Vancleef, R. Lories, R. K. Korhonen, P. Aerts, S. Van Wassenbergh, I. Jonkers

This study uses a rat model to assess joint and tissue mechanics in post-traumatic osteoarthritis, finding no increased mechanical loading in the medial compartment despite structural changes.

bioRxiv · Jun 27, 2024 · PreprintBioengineering

Hypoxia induces transcription of DOT1L in articular cartilage to protect against osteoarthritis

A. De Roover, A. Escribano, F. Cornelis, C. Cherifi, L. Casas-Fraile, A. Sermon, F. Cailotto, R. Lories, S. Monteagudo

This study identifies hypoxia-induced DOT1L transcription as a protective mechanism against osteoarthritis and shows that hypoxia mimetics can restore DOT1L function and slow disease progression.

bioRxiv · May 14, 2021Cell Biology

ANP32A represses Wnt signaling across tissues tissues thereby protecting against joint and heart disease

S. Monteagudo, F. Cornelis, X. Wang, A. De Roover, T. Peeters, J. Quintiens, A. Sermon, R. Coutinho de Almeida, I. Meulenbelt, R. Lories

This study identifies ANP32A as a repressor of Wnt signaling that protects against joint and heart disease by inhibiting Wnt target genes and oxidative stress.

bioRxiv · Apr 4, 2021Cell Biology

Radiosafe micro-computed tomography for longitudinal evaluation of murine disease models

N. Berghen, K. Dekoster, E. Marien, J. Dabin, A. Hillen, J. Wouters, J. Deferme, T. Vosselman, E. Tiest, M. Lox, J. Vanoirbeek, E. De Langhe, R. Bogaerts, M. Hoylaerts, R. Lories, G. Vande Velde

The paper evaluates the safety of repeated micro-CT scans in mice, finding that optimized protocols reduce radiation dose without affecting disease models or blood cell counts.

bioRxiv · Nov 20, 2019Physiology