Author

L. Chiou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A.-P. Lin· 1 shared C. Jaafar· 1 shared G. Huelgas-Morales· 1 shared J. Khalife· 1 shared P. Dahia· 1 shared P. Ethiraj· 1 shared R. Aguiar· 1 shared S. Arya· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A.-P. Lin

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1 paper

Recent·Most cited

IRF8-mutant B cell lymphoma evades immunity through a CD74-dependent deregulation of antigen processing and presentation in MHC CII complexes

Z. Qiu, J. Khalife, A.-P. Lin, P. Ethiraj, C. Jaafar, L. Chiou, G. Huelgas-Morales, S. Aslam, S. Arya, Y. Gupta, P. Dahia, R. Aguiar

This study shows that IRF8 mutations in DLBCL lymphomas impair antigen processing and presentation by reducing CD74 and HLA-DM, leading to immune evasion and increased tumor burden.

bioRxiv · Oct 14, 2023Cancer Biology