Author

L. D. Brennan

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

B. Huang· 1 shared C. R. Carlson· 1 shared D. Brown· 1 shared G. J. Narlikar· 1 shared H. Khoo· 1 shared M. M. Keenen· 1 shared R. Renger· 1 shared S. Redding· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

B. Huang

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1 paper

Recent·Most cited

HP1 proteins compact DNA into mechanically and positionally stable phase separated domains

M. M. Keenen, D. Brown, L. D. Brennan, R. Renger, H. Khoo, C. R. Carlson, B. Huang, S. W. Grill, G. J. Narlikar, S. Redding

This study shows HP1 proteins form phase-separated DNA condensates that are mechanically stable but can be dissolved by HP1β, with differences in DNA compaction linked to their disordered regions.

bioRxiv · Oct 30, 2020Biochemistry