Estimates of persistent inward currents are reduced in upper limb motor units of older adults
A. S. Hassan, M. E. Fajardo, M. Cummings, L. M. McPherson, F. Negro, J. P. Dewald, C. Heckman, G. E. Pearcey
This study finds reduced persistent inward currents in older adults' motor units, linked to age-related decline in monoaminergic input and potential mechanisms for reduced firing rates and weakness.
bioRxiv · Jun 18, 2021Physiology