The synergic role of actomyosin architecture and biased detachment in muscle energetics: insights in cross bridge mechanism beyond the lever-arm swing
L. Marcucci, H. Fukunaga, T. Yanagida, M. Iwaki
This study combines experiments and simulations to show that geometrical hindrance and biased detachment synergistically enhance muscle contraction efficiency by increasing ATP-ase rate during contraction.
bioRxiv · Mar 23, 2021Biophysics