Author

T. Yanagida

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:imaging· 1

Frequent Co-Authors

M. Iwaki· 3 shared H. Fukunaga· 2 shared K. Fujita· 2 shared K. Ikezaki· 2 shared M. Ohmachi· 2 shared H. Takagi· 1 shared L. Marcucci· 1 shared T. Washio· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 23 mutual co-author links

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3 shared papersBiophysics

M. Iwaki

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dynamic coordination of the lever-arm swing of human myosin II in thick filaments on actin

H. Fukunaga, T. Washio, K. Fujita, M. Ohmachi, H. Takagi, K. Ikezaki, T. Yanagida, M. Iwaki

This study uses high-speed atomic force microscopy to observe myosin II lever-arm coordination in synthetic thick filaments, revealing how structural mismatches enhance contraction efficiency.

bioRxiv · Aug 30, 2023 · PreprintBiophysics

The synergic role of actomyosin architecture and biased detachment in muscle energetics: insights in cross bridge mechanism beyond the lever-arm swing

L. Marcucci, H. Fukunaga, T. Yanagida, M. Iwaki

This study combines experiments and simulations to show that geometrical hindrance and biased detachment synergistically enhance muscle contraction efficiency by increasing ATP-ase rate during contraction.

bioRxiv · Mar 23, 2021Biophysics

Direct visualization of human myosin II force generation using DNA origami-based thick filaments

K. Fujita, M. Ohmachi, K. Ikezaki, T. Yanagida, M. Iwaki

This study directly visualizes human myosin II force generation using DNA origami-based thick filaments and single-molecule imaging, revealing key dynamics of the lever-arm swing and actin interaction.

bioRxiv · May 13, 2019Biophysics