Author

L. P. Feilen

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Biochemistry· 1

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Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Assay:structural biology· 1

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A. Fukumori· 1 shared H. Steiner· 1 shared M. Zacharias· 1 shared R. Feederle· 1 shared S.-Y. Chen· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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1 shared paperBiochemistry

A. Fukumori

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1 paper

Recent·Most cited

Active site geometry stabilization of a presenilin homolog by the lipid bilayer promotes intramembrane proteolysis

L. P. Feilen, S.-Y. Chen, A. Fukumori, R. Feederle, M. Zacharias, H. Steiner

This study shows that the lipid bilayer stabilizes the active site geometry of the intramembrane protease PSH, enhancing its catalytic activity compared to micelles.

bioRxiv · Jan 10, 2022Biochemistry