Cancer BiologybioRxiv
TRIB3 silencing promotes the downregulation of Akt pathway and PAX3-FOXO1 in high-risk rhabdomyosarcoma
G. O. Gallo-Oller, G. Pons, J. Sansa-Girona…·J. Roma
This study shows TRIB3 silencing reduces Akt pathway activity and PAX3-FOXO1 levels in high-risk rhabdomyosarcoma, leading to decreased tumor growth and improved survival.
DOI 10.1186/s40164-024-00503-9