Increased drug-seeking and vulnerability to relapse after escalation of nicotine intake in male and female rats
Kevin Letort, Laetitia Lageyre, Serge H. Ahmed, Karine Guillem
This study shows that nicotine escalation in rats leads to increased drug-seeking and relapse vulnerability, with no significant sex differences.
bioRxiv · Sep 14, 2025 · PreprintNeuroscience