Author

Larry V. Pearce

National Cancer Institute

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Christina R. RossiD· 1 shared Jack D. SanfordiD· 1 shared Karol SzczepanekiD· 1 shared Kent W. HunteriD· 1 shared Tinghu Qiu· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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1 shared paperCancer Biology

Christina R. RossORCID

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1 paper

Recent·Most cited

Investigating the genomic landscape of mouse models of breast cancer metastasis

Christina R. Ross, Karol Szczepanek, Jack D. Sanford, Tinghu Qiu, Larry V. Pearce, Kent W. Hunter

This study examines four mouse breast cancer models to show that oncogenic drivers influence metastasis-specific copy number variations and gene expression, while genetic background also plays a significant role.

bioRxiv · Jan 15, 2025 · PreprintCancer Biology