Bone marrow-on-a-chip: Emulating the human bone marrow
Stefan Sieber, Annika Winter, Johanna Wachsmuth, Rhiannon David, Maria Stecklum, Lars Hellmeyer, Lorna Ewart, Uwe Marx, Roland Lauster, Mark Rosowski
This paper describes a bone marrow-on-a-chip model that supports long-term cultivation and differentiation of human hematopoietic stem and progenitor cells, demonstrating its utility for drug testing and transplantation studies.
bioRxiv · Nov 21, 2018 · PreprintBioengineering