Author

Lauren E DiPaola

Center for Theoretical Biological Physics

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Biophysics· 1

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Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:simulation· 1 Approach:statistical model· 1 Research Focus:transcription & RNA processing· 1

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Antonio Bento de Oliveira JunioriD· 1 shared Dimanthi N PereraiD· 1 shared José N. OnuchiciD· 1 shared Matheus F. MelloiD· 1 shared Ryan R. ChengiD· 1 shared Vinícius G. ContessotoiD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperBiophysics

Antonio Bento de Oliveira JuniorORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintAug 25, 2026

The compartmental polarization of interphase human chromosomes within the nucleus: A mechanism for transcriptional regulation of large chromosomes

Matheus F. Mello, Dimanthi N Perera, Lauren E DiPaola…·Ryan R. Cheng

The paper uses simulations and imaging data to show that lamina-associated chromosomes have polarized compartmentalization and enhanced euchromatin contacts, potentially improving transcription for large chromosomes.

DOI 10.64898/2026.08.21.746281

humanbulk RNA-seq

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