Dynamics of circulating tumor cell subsets defined by PSMA and EpCAM predict survival in metastatic castration-resistant prostate cancer patients treated with 177Lu-PSMA-617
Madeline J. Lee, Lauren Yu, Nicholas A. Zorko, Scott M. Dehm, Justin H. Hwang, Justin M. Drake, Emmanuel S. Antonarakis, Ali T. Arafa
The paper assesses CTC subset dynamics in mCRPC patients treated with 177Lu-PSMA-617 and finds that changes in PSMA and EpCAM-expressing CTCs correlate with survival outcomes.
bioRxiv · Sep 16, 2026 · PreprintCancer Biology