Author

Justin M. Drake

University of MinnesotaORCID 0000-0002-8329-7748Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Justin H. HwangiD· 3 shared Ali T. ArafaiD· 2 shared Emmanuel S. AntonarakisiD· 2 shared Hannah E. BergomiD· 2 shared Scott M. DehmiD· 2 shared Zoi E. SycheviD· 2 shared Abderrahman DayiD· 1 shared Alec Horrmann· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCancer Biology

Justin H. HwangORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dynamics of circulating tumor cell subsets defined by PSMA and EpCAM predict survival in metastatic castration-resistant prostate cancer patients treated with 177Lu-PSMA-617

Madeline J. Lee, Lauren Yu, Nicholas A. Zorko, Scott M. Dehm, Justin H. Hwang, Justin M. Drake, Emmanuel S. Antonarakis, Ali T. Arafa

The paper assesses CTC subset dynamics in mCRPC patients treated with 177Lu-PSMA-617 and finds that changes in PSMA and EpCAM-expressing CTCs correlate with survival outcomes.

bioRxiv · Sep 16, 2026 · PreprintCancer Biology

Proteomic profiling of extracellular vesicles distinguishes prostate cancer molecular subtypes

Megan Ludwig, Ali T. Arafa, Saasha Vinoo, Jason C. Jones, Abderrahman Day, Hannah E. Bergom, Zoi E. Sychev, Alec Horrmann, Nicholas M. Levinson, Scott M. Dehm, Emmanuel S. Antonarakis, Justin H. Hwang, Justin M. Drake

This study uses proteomic profiling of extracellular vesicles to distinguish prostate cancer subtypes and identify subtype-specific biomarkers.

Journal of Extracellular Vesicles · Oct 1, 2025Peer-reviewedCancer Biology

SOX2 utilizes FOXA1 as a heteromeric transcriptional partner to drive proliferation in therapy-resistant prostate cancer

John T. Phoenix, Audris Budreika, Devin A. Schmeck, Raymond J. Kostlan, Marina G. Ferrari, Kristen S. Young, Charles S. Rogers, Carleen D. Deegan, Marcus W. Bienko, Hannah E. Bergom, Ella Boytim, Ryan M. Brown, Julia A. Walewicz, Shreya K. Bhagi, Leigh Ellis, , Steven Kregel

This study identifies SOX2 and FOXA1 as a transcriptional partnership driving proliferation and lineage plasticity in therapy-resistant prostate cancer.

bioRxiv · Jul 18, 2025 · PreprintCancer Biology

Dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-mutant prostate cancer

Mia E. Hofstad, Andrea Woods, Karla Parra, Zoi E. Sychev, Alice Mazzagatti, Xiaofang Huo, Lan Yu, Collin Gilbreath, Wei‐Min Chen, Anthony J. Davis, Peter Ly, Justin M. Drake, Ralf Kittler

This study shows that dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-deficient prostate cancer cells, with Compound B effectively achieving this in vitro and in vivo.

Oncogene · Mar 21, 2025Peer-reviewedCancer Biology