Optimizing photoautotrophic production of soluble 3-hydroxybutyrate in Synechocystis sp. PCC 6803 through combinatorial translational tuning
Lauri Kakko, Dorota Muth‐Pawlak, Pekka Patrikainen, Eva–Mari Aro, P. Kallio
This paper enhances 3-hydroxybutyrate production in Synechocystis sp. PCC 6803 by optimizing translational regulation of key pathway enzymes, achieving high titers in photoautotrophic conditions.
bioRxiv · Jun 3, 2026 · PreprintSynthetic Biology