The dietary ellagitannin metabolite urolithin A is produced by a molybdenum-dependent dehydroxylase encoded by prevalent human gut Enterocloster spp.
Reilly Pidgeon, Sacha Mitchell, Michael Shamash, Layan Suleiman, Lharbi Dridi, Corinne F. Maurice, Bastien Castagner
The paper identifies Enterocloster spp. and the ucd operon as key producers of urolithin A from dietary ellagitannins using multi-omics approaches.
Nature Communications · Jan 24, 2025Peer-reviewedMicrobiology