Author

Lei Cai

Beijing University of Chemical Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Chong Gao· 1 shared Feng YaniD· 1 shared Fengli XuiD· 1 shared Hao Zhang· 1 shared Heping ChengiD· 1 shared Hua HaniD· 1 shared Jiaming Kong· 1 shared Jiangli YangiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBioinformatics

Chong Gao

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3 papers

Recent·Most cited

A disease dynamics atlas forecasts patient states and maps molecular programs in ALS

Zizhang Li, Chong Gao, Jiaming Kong, Yuting Fu, Shan Wen, 李光鹏, Ye Cao, Yunlin Fu, Hao Zhang, Shikai Jia, Xiaojing Liu, Jiangli Yang, Lei Cai, Feng Yan, Xiaodong Liu, Luyi Tian

The paper develops DynaALS, a disease dynamics atlas for ALS that maps patient states and molecular programs using longitudinal medical records and multi-omics data.

bioRxiv · Aug 11, 2026 · PreprintBioinformatics

ROMO1 loss in cholinergic neurons induces mitochondrial ultrastructural damage and ALS-like neuromuscular degeneration

Wei Nie, Zhiwen Jing, Linling Cheng, Linlin Li, Yuxiao Bai, Fengli Xu, Sihan Li, Limei Lin, Xiaohui Dong, Liping Yu, Lei Cai, 潘秉兴, Hua Han, Heping Cheng, Xianhua Wang

This study shows that loss of ROMO1 in cholinergic neurons causes mitochondrial damage and ALS-like symptoms in mice.

中国科学通报：英文版 · Aug 1, 2026Peer-reviewedNeuroscience

DeepSV: Accurate calling of genomic deletions from high throughput sequencing data using deep convolutional neural network

Lei Cai, Yufeng Wu, Jingyang Gao

DeepSV uses a deep convolutional neural network to accurately call long deletions from sequencing data, outperforming existing methods on the 1000 Genomes Project data.

BMC Bioinformatics · Dec 1, 2019Peer-reviewedBioinformatics