Author

Lekshmi Dharmarajan

SIB Swiss Institute of Bioinformatics

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1 Organism:yeast· 1

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Fabian RudolfiD· 1 shared Hans‐Michael KaltenbachiD· 1 shared Jörg StellingiD· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperSystems Biology

Fabian RudolfORCID

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1 paper

Recent·Most cited

A simple and flexible computational framework for inferring sources of heterogeneity from single-cell dynamics

Lekshmi Dharmarajan, Hans‐Michael Kaltenbach, Fabian Rudolf, Jörg Stelling

The paper introduces a two-stage method to estimate dynamic nonlinear mixed effects models from single-cell time-lapse data, demonstrating accuracy and scalability with yeast endocytosis data.

Cell Systems · Jan 1, 2019Peer-reviewedSystems Biology