Author

Lena Fraedrich

Leibniz University Hannover

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

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Approach:machine learning (classical)· 1 Research Focus:protein design· 1 Assay:proteomics· 1

Frequent Co-Authors

Li WaniD· 1 shared Mahdi Bagherpoor HelabadiD· 1 shared Martin J. WeissenborniD· 1 shared Sarel Jacob FleishmaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

Li WanORCID

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1 paper

Recent·Most cited

Combining Stability-Centered Atomistic Design with Machine Learning for Targeted Enzyme Optimization

Li Wan, Mahdi Bagherpoor Helabad, Lena Fraedrich, Sarel Jacob Fleishman, Martin J. Weissenborn

This paper introduces MLEE, a machine learning-assisted enzyme engineering workflow that improves hit rates for high-fitness enzyme variants compared to traditional methods.

bioRxiv · Jul 21, 2026 · PreprintBiochemistry