Reduced cerebellar Gq-protein signaling elicits early onset spatial navigation deficits in a SCA6 mouse model
Michelle Grömmke, Hannah Schulte, Candy D. C. Theis, Lena Nonnweiler, Melanie D. Mark
This study shows that SCA6 mice exhibit early cognitive deficits in spatial navigation linked to reduced Gq-protein signaling in the cerebellum, preceding motor impairments.
bioRxiv · Sep 12, 2023 · PreprintNeuroscience