Author

Leo Shen

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Systems Biology· 1

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Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Mingyu YangiD· 1 shared Na LiiD· 1 shared Rong FaniD· 1 shared Zhiliang BaiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperSystems Biology

Mingyu YangORCID

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1 paper

Recent·Most cited

Single-cell foundation models predict durable CAR T response despite imperfect cell annotation

Leo Shen, Zhiliang Bai, Mingyu Yang, Na Li, Rong Fan

The paper uses single-cell foundation models to predict durable CAR T response from pre-infusion scRNA-seq data, achieving high accuracy without requiring perfect cell annotation.

bioRxiv · Jul 23, 2026 · PreprintSystems Biology