Senolytic therapy combining Dasatinib and Quercetin restores the chondrogenic phenotype of human osteoarthritic chondrocytes by promoting the release of pro-anabolic mediators
Svenja Maurer, Valeria Kirsch, Leonie Ruths, Rolf Erwin Brenner, Jana Riegger
Senolytic therapy with Dasatinib and Quercetin improves chondrocyte function in osteoarthritis by reducing senescence-associated secretory phenotype factors and increasing anabolic gene expression.
Aging Cell · Oct 14, 2024Peer-reviewedCell Biology