Inflammation-driven cellular selection impacts X-linked mosaicism in the epidermis
Eleni Angelopoulou, Karan Gandhi, Marjolein van Wolfswinkel, Leonie Schmautz, Iñigo Oyarzun, Sarah Nowosadtko, Irmgard Fischer, Viktor Schwartz, Johannes Griss, Stephanie J. Ellis
This study shows inflammation drives X-linked mosaicism resolution in the epidermis by eliminating mutant cells, with wild-type cells compensating for loss.
bioRxiv · Oct 10, 2026 · PreprintCell Biology