Noninvasive enrichment of circulating tumor biomarkers in a mouse model of diffuse midline glioma using focused ultrasound
Dingyue Zhang, Yimei Yue, Yan Gong, Leqi Yang, Kevin Xu, Jinyun Yuan, Hong Chen
This study shows that focused ultrasound with microbubbles can increase circulating tumor biomarkers in blood and CSF of a mouse DMG model, with enrichment varying by source, analyte type, and marker.
bioRxiv · Dec 5, 2025 · PreprintBioengineering