HIF-1α Contributes to the Progression of Chronic Obstructive Pulmonary Disease
Kedong Zhang, Feng Zhou, Caixia Zhu, Liang Yuan, Defu Li, Jian Wang, Wenju Lu
This study investigates the role of HIF-1 in COPD progression using digoxin as an inhibitor, showing its protective effects against inflammation and EMT through the HIF-1/TGF-β1/Smad3 pathway.
bioRxiv · Jan 9, 2022 · PreprintMolecular Biology