Author

Liangwei Guo

Fudan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:proteomics· 1

Frequent Co-Authors

Gaoxing Guo· 1 shared Jiaqiang QianiD· 1 shared Lei WangiD· 1 shared Qiang HuangiD· 1 shared Xiaoming HeiD· 1 shared Xinzhou Qian· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Gaoxing Guo

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1 paper

Recent·Most cited

De novo design of protein-binding aptamers through deep reinforcement learning assembly of nucleic acid fragments

Gaoxing Guo, Liangwei Guo, Jiaqiang Qian, Xiaoming He, Xinzhou Qian, Lei Wang, Qiang Huang

This paper introduces AiDTA, a deep reinforcement learning method for de novo design of protein-binding aptamers, achieving high-affinity DNA aptamers for disease-related proteins.

bioRxiv · Jun 1, 2025 · PreprintBioinformatics