High diversity, turnover, and structural constraints characterize TCR α and β repertoire selection
Larisa Kamga, Anna Gil, Inyoung Song, Ramakanth Chirravuri, Nuray Aslan, Dario Ghersi, Lawrence J. Stern, Liisa K. Selin, Katherine Luzuriaga
The paper examines TCR α and β repertoire dynamics during EBV infection, finding that persistent clonotypes are highly expanded in acute infection and replaced by new clonotypes in convalescence.
bioRxiv · Sep 29, 2018 · PreprintImmunology