IgGM2: An All-Atom Foundation Model for Adaptive Immune Receptor Design
J J Ma, Fandi Wu, Lin Yao, J Gao, Rubo Wang, Qifeng Li, Nianzu Yang, Songlin Jiang, Dawei Huang, Xiaoyong Pan, Yiheng Zhu, Tingjun Hou, Jianhua Yao, Junchi Yan
IgGM2 is an all-atom foundation model for immune receptor design that jointly predicts CDR sequences and full-atom structures, outperforming existing methods in structure prediction and sequence design benchmarks.
bioRxiv · Jul 9, 2026 · PreprintBioinformatics