J Gao

The paper identifies two distinct ADHD biotypes using brain imaging and transcriptomic data, showing different developmental, molecular, and treatment responses.

This paper constructs sex-specific lifespan brain charts using neuroimaging data from 59,915 individuals, revealing dynamic sex differences in brain development and improving detection of neuropsychiatric abnormalities.

This paper develops a compact genome-editing system in Bacillus subtilis using the TAM-independent nuclease TasR, enabling efficient gene deletion, integration, and iterative editing.

IgGM2 is an all-atom foundation model for immune receptor design that jointly predicts CDR sequences and full-atom structures, outperforming existing methods in structure prediction and sequence design benchmarks.

MacaSurfer provides a unified framework for automated surface-volume mapping of the macaque brain across age and sites, showing high consistency and robustness.