A multi-pore model of the blood-brain barrier tight junction strands recapitulates the permeability features of wild-type and mutant claudin-5
Alessandro Berselli, Giulio Alberini, Linda Cerioni, Fabio Benfenati, Luca Maragliano
The paper models the blood-brain barrier tight junctions using multi-pore structures and shows that multi-Pore I replicates the permeability effect of a Cldn5 mutation.
Protein Science · Aug 27, 2025Peer-reviewedNeuroscience