Mitochondrial acid-sensing ion channel 1a deficiency induces mitochondrial dysfunction in pulmonary arterial smooth muscle cells
Megan N. Tuineau, Lindsay M. Herbert, Heaven E. Medina, Jay S. Naik, Thomas C. Resta, Nikki L. Jernigan
This study shows that loss of mtASIC1a in PASMCs under chronic hypoxia leads to mitochondrial dysfunction and apoptosis resistance.
American Journal of Physiology-Lung Cellular and Molecular Physiology · Feb 25, 2026Peer-reviewedPhysiology