The Interaction of UBR4, LRP1, and OPHN1 in Refractory Epilepsy: Drosophila Model to Investigate the Oligogenic Effect on Epilepsy
Rui-Na Huang, Si-Yuan Luo, Tao Huang, Xinyue Li, Fan-Chao Zhou, Ling-Ying Li, Ze-Ru Chen, Shengqiang Chen, Bin Tang, Jing‐Da Qiao
The paper investigates the epileptogenic effects of UBR4, LRP1, and OPHN1 mutations using Drosophila models and identifies negative gene interactions contributing to seizure susceptibility.
bioRxiv · Oct 25, 2024 · PreprintNeuroscience