Augmentation of nonsense mediated decay by rapamycin
Rocio Teresa Martinez-Nunez, Doyle Coyne, Linnea Jansson, Miles Rush, Hanane Ennajdaoui, Tilman Sanchez-Elsner, Jeremy Sanford
This study shows that rapamycin enhances NMD by altering mRNP composition, reducing PTC-containing mRNA levels and affecting polyribosome dynamics.
bioRxiv · Oct 28, 2015Molecular Biology