Multi-Omics Data of Perturbation Studies are Determined by Memory Effects from Subculture
Patricia Bortel, Gerhard Hagn, Lukas Skos, Andrea Bileck, Verena Paulitschke, Philipp Paulitschke, Lion Gleiter, Thomas T. Mohr, Christopher Gerner, Samuel M. Meier
The paper shows that subculture memory effects increase variation in omics data from perturbation studies, improving deconvolution and revealing causal networks.
bioRxiv · Feb 13, 2023 · PreprintSystems Biology