MECP2 Mutations Rewire Human ESC Fate and Bias Cortical Lineage Commitment
Marion Guillon, Margaux Brin, Elodie Gabet, Justine Gromaire, Mathéa Bernard, Laetitia Laurent, Theo Rabin, Lisa Bianchin, Marie Veziano, Julie Kloda, Alexia Bernard, Laila Asali, Yi Liu, Anthony Flamier
This study shows MECP2 mutations alter human ESC fate and bias cortical lineage commitment by affecting ZFP42 and EMX1 expression.
Stem Cell Reports · Apr 23, 2026Peer-reviewedNeuroscience