Quantitative mapping of methionine sensitivity to oxidation in the copper-bound PcuC chaperone
Lionel Tarrago, Lise Molinelli, Maya Belghazi, Mathilde Tribout, David Lemaire, Pierre Legrand, Sandrine Grosse, David Pignol, Monique Sabaty, Thierry Tron, Pascal Arnoux
The paper quantifies methionine oxidation sensitivity in apo- and Cu-bound PcuC using a methionine-specific probe, showing increased oxidation of coordinating methionines upon Cu binding.
Redox Biology · Jan 19, 2026Peer-reviewedBiochemistry