Methionine matters: a common mechanism of viral inhibition of host defense identified via AI-assisted molecular dynamics
Skye J Bixler, Gregory A. Babbitt, Liv K Caspersson, Maureen C. Ferran
The paper identifies a common mechanism across diverse viruses that use methionine residues to inhibit host defense by blocking the Rae1-Nup98 complex, supported by AI-assisted molecular dynamics.
bioRxiv · Sep 19, 2025 · PreprintMicrobiology