Graphene Device for High-Temperature Crystallography Visualizes How Enzymatic Reactivity is Rooted in Ensemble Probability
R.A.P. Padua, Sarthak Saha, Christiana Ntangka, José Fernando Ruggiero Bachega, Logan Chen, Aina E. Cohen, Sarah L. Perry, Dorothee Kern
The paper develops a graphene device for high-temperature crystallography to study enzymatic reactivity across temperature ranges, revealing how transition state ensembles relate to catalytic rates.
bioRxiv · Aug 21, 2026 · PreprintBiophysics