Intranasal Dantrolene Nanoparticles for Treatment of Amyotrophic Lateral Sclerosis as a Disease-Modifying Drug
Piplu Bhuiyan, Yutong Yi, Betty Wei, Allen Yan, Lola Dong, Huafeng Wei
This study shows that intranasal dantrolene nanoparticles significantly improve neurological function, motor coordination, muscle strength, and survival in SOD1-G93A ALS mice.
bioRxiv · May 21, 2025 · PreprintPharmacology & Toxicology