Chronic alcohol exposure induces cerebral microbleeds by TGF-β1/Smad signaling pathway mediated remodeling of cerebral small vessels
Hengjian Lu, Hongxuan Wang, Xiangpen Li, Xinrou Lin, Chenguang Li, Wanru Chen, Lubin Zou, Jingrui Pan, Xiaoni Zhang, Lei He, Xiaoming Rong, Ying Peng
This study shows chronic alcohol exposure causes cerebral microbleeds through TGF-β1/Smad signaling-driven ECM remodeling in small vessels, with potential therapeutic implications.
bioRxiv · Feb 7, 2024 · PreprintMolecular Biology