Novel fat-taste enhancers modulate functional connectivity of the reward system following sustained activation of gustatory pathways in mice
Lidia Cabeza, Lucas Jantzen, Christophe Houdayer, Émmanuel Haffen, Aziz Hichami, Naim A. Khan, Vincent Van Waes
This study shows that fat-taste enhancers NKS-3 and NKS-5 reduce fat intake and body weight in obese mice without adverse effects, suggesting a potential therapeutic strategy for obesity.
bioRxiv · Sep 11, 2025 · PreprintNeuroscience