Leg blood flow and muscle oxygenation are reduced when exercising with loads >=40% 1RM compared to loads <=30% 1RM due to increases in contraction induced intramuscular pressure
Matthew D Fliss, Kyla Coates, Sam J Hillen, Gabby Yarema, Lucas Wiens, Jem I Arnold, Aidan Comeau, Viviana Shiffman, Jamie Burr, Martin MacInnis, Robert Boushel, Michael Koehle, Cameron J Mitchell
This study shows that leg blood flow and muscle oxygenation decrease during resistance exercise at loads ≥40% 1RM compared to ≤30% 1RM due to increased intramuscular pressure.
bioRxiv · Nov 2, 2026 · PreprintPhysiology