DOT1L Methyltransferase Activity Preserves SOX2-Enhancer Accessibility And Prevents Activation of Repressed Genes In Murine Stem Cells
Fernando Daniel Berdaguer Ferrari, Laura Arrigoni, Henriette Franz, Ludmila Butenko, Eirini Trompouki, Tanja Vogel, Thomas Manke
This study investigates how DOT1L methyltransferase activity affects chromatin states and gene expression during neuronal differentiation of mouse embryonic stem cells.
bioRxiv · Feb 3, 2020 · PreprintGenomics