A Minimally Perturbative DARPin Probe for Quantitative Fluorescence Imaging of the Human TCR-CD3 Complex
Marti Pons Romero, Barbora Kalousková, Jovana Kloimwieder, Alejandro Linares, Anezka Majkova, Lukas Riedl, Caroline Kopittke, Marina Bishara, Mario O. Brameshuber, Eva Sevcsik
This paper develops a minimally perturbative DARPin probe for quantitative fluorescence imaging of the human TCR-CD3 complex, showing it preserves antigen sensitivity and enables advanced imaging techniques.
bioRxiv · Sep 27, 2026 · PreprintBiophysics