Author

Lyne Desautels

Institut National de Santé Publique du Québec

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandre K. DubéiD· 1 shared Alicia PageauiD· 1 shared Christian R. LandryiD· 1 shared François D. RouleauiD· 1 shared Philippe J. DufresneiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

Alexandre K. DubéORCID

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1 paper

Recent·Most cited

Predicting antifolate resistance in the unculturable fungal pathogen Pneumocystis jirovecii

François D. Rouleau, Alexandre K. Dubé, Alicia Pageau, Lyne Desautels, Philippe J. Dufresne, Christian R. Landry

This paper trains a machine learning model to predict antifolate resistance mutations in Pneumocystis jirovecii using experimental data and computational modeling, finding mutations that confer resistance to trimethoprim-sulfamethoxazole.

PLoS Genetics · May 27, 2026Peer-reviewedBiochemistry