Loss of INPP5E affects photoreceptor outer segment membrane biogenesis in iPSC-derived human retinal organoids
Katherine Whiting, Mariam G. Aslanyan, Lynn van Summeren, Tina Beyer, Katrin Dahlke, Thomas Theil, Karsten Boldt, Ronald Roepman
This study shows that loss of INPP5E in human retinal organoids disrupts photoreceptor outer segment membrane biogenesis and alters protein localization.
Journal of Cell Science · Jun 30, 2026Peer-reviewedCell Biology