Glucocorticoid and Mineralocorticoid Receptors Jointly Promote Vascular Development in Kidney Organoids
Cory P. Johnson, Hannah M. Somers, Sophie E. Craig, J. Heath Fuqua, Lynne Beverly-Staggs, Kailee E. Tanaka, Sydney M Brown, Charles H. Toulmin, Matthew D. Cox, Joel H. Graber, Melissa S. Maginnis, Hermann G. Haller
This study shows that glucocorticoid and mineralocorticoid receptors promote vascular development in kidney organoids through endothelial cell differentiation and vessel formation.
bioRxiv · Sep 3, 2025 · PreprintDevelopmental Biology