Mapping binding landscape of allosteric inhibitor G6PDi-1 on human G6PD
Amit Kumawat, Andrea Perra, M Faubel Serra, Giorgia Zedda, Marta Anna Kowalik, Andrea Marco Caddeo, Paolo Ruggerone
This study investigates how the allosteric inhibitor G6PDi-1 affects G6PD activity by combining biochemical assays and computational methods, revealing binding sites and allosteric effects that disrupt oligomerization.
The Journal of Physical Chemistry Letters · Jun 18, 2026Peer-reviewedBiophysics