Computationally Driven Design of Novel BACE-1 Inhibitors for Alzheimer's Disease
M. M. Chinn, D. L. Mateos, M. A. Riley, J. B. Siegel
This study designs new BACE-1 inhibitors using computational modeling, showing improved docking scores compared to Verubecestat for Alzheimer's disease treatment.
bioRxiv · Nov 15, 2023 · PreprintBiochemistry