S494 O-glycosylation site on the SARS-COV-2 RBD Affects the Virus Affinity to ACE2 and its Infectivity; A Molecular Dynamics Study
S. Rahnama, M. Azimzadeh Irani, M. Amininasab, R. Ejtehadi
This study uses molecular dynamics simulations to show that an O-glycosylation site on the SARS-CoV-2 RBD affects virus affinity to ACE2 and infectivity by stabilizing RBD-ACE2 interactions.
bioRxiv · Sep 12, 2020Biophysics